2009: Perceived health status in multiple sclerosis patients

Project title 2009: Perceived health status in multiple sclerosis patients
Promotor Prof. Dr. Johan W. Groothoff
Co-promotors Assoc. Prof. Dr. Jitse P. van Dijk, MDAssoc. Prof. Zuzana Gdovinova, MD, Dr. Iveta Rajnicova-Nagyova, Dr. Berrie Middel
PhD student Martina Chylova-Krokavcova
Time period PhD thesis defended on 29.06.2009
Financial support Bilateral agreement between P.J.Safarik University and University of Groningen; and APVV-20-038305
Description This study on Multiple Sclerosis focuses on the use of the physical and mental health dimensions of self perceived health measured by the SF-36 that are linked to clinical data and psychosocial factors. A review of the articles described that the more disabled and older the MS patients, the poorer their perceived health status was and the more depressed the patients, the worse their perceived health status was. MS patients who reported good self rated health were more likely to be employed, less disabled and less anxious. Furthermore, social support from significant others is positively associated with their physical health status, while social support from family and friends was found to have more positive consequences on the mental health status in MS patients. Mastery is a meaningful variable determining perceived health status, especially in MS patients of 45 years and over. The role of depression was present with regard to perceived health status, mainly to perceived physical health status in the older group and to perceived mental health status in the younger one. The role of anxiety was more important in younger MS patients than among older patients with regard to their perceived health status. Supporting social ties and relationships between MS patients and others are very important. Furthermore, health care professionals` education and counselling in supporting the coping strategies of MS patients are essential for good patient management.
Main findings The more disabled, older and more depressed MS patiens were, the poorer their perceived health status was. Mastery as the sense of personal control which affects life appeared as a meaningful variable determining perceived health status, especially in MS patients of 45 years and over. Neurologists` education and counselling in supporting the coping strategies of MS patients are essential for good patient management. Social support from significant others positively influences physical health status, while social support from family and friends was found to have more positive consequences on mental health status in MS patients. MS patients with good self-rated health are more likely to be employed, even after adjusting for age, gender, education, functional disability, disease duration, depression and anxiety.Mastery, social support and employment status had a beneficial impact on health status in MS patients.
Dissertations http://dissertations.ub.rug.nl/faculties/medicine/2009/m.krokavcova/